EGFR-IN-109

CAT: 0931-T86360-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T86360-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

3019971-97-9

Target

Apoptosis, Caspase, Bcl-2 Family, EGFR

Related Pathways

JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis, Proteases/Proteasome, Apoptosis

Bioactivity

EGFR-IN-109 (compound 4), an EGFR inhibitor, displays IC 50 values of 25.8 nM for EGFR WT and 182.3 nM for EGFR T790M. This compound halts the growth of cancer cells at the G2/M phase and triggers both early and late apoptosis. It is applicable in cancer research [1].

Smiles

O=C1C=2C3=C(SC2NC(CNN)=N1)CC(C)CC3

Molecular Formula

C12H16N4OS

Molecular Weight

264.35

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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EGFR-IN-109

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