Ebselen derivative 1

• Target:

  Apoptosis|||Ferroptosis

• Related Pathways:

  Apoptosis

• Bioactivity:

  Ebselen derivative 1 (Compound 19), an orally active glutathione peroxidase (GPx) mimic, exhibits notable protective effects against cisplatin-induced hair cell (HC) damage in both in vitro and in vivo settings. It significantly reduces oxidative stress, apoptosis, and ferroptosis in hair cells, making it useful in the study of cisplatin-induced hearing loss [1].

• Smiles:

  O (C) C1=C2C (C (=O) N ([Se]2) C=3C=CC=NC3) =CC=C1

• Molecular Formula:

  C13H10N2O2Se

• Molecular Weight:

  305.19

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3030492-59-9