Ebselen

• Target:

  HIV Protease|||Phosphatase|||Calcium Channel|||COX|||Virus Protease

• Related Pathways:

  Proteases/Proteasome|||Immunology/Inflammation|||Neuroscience|||Metabolism|||Membrane transporter/Ion channel|||Microbiology/Virology

• Purity:

  0.9994

• Bioactivity:

  Ebselen (CCG-39161) is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is thereby able to prevent cellular damage induced by reactive oxygen species (ROS) . In addition, this agent inhibits the activity of a variety of enzymes including nitric oxide synthase (NOS), 5-lipoxygenase, cyclooxygenase, protein kinase C (PKC), NADPH oxidase and gastric H+/K+-ATPase. Furthermore, ebselen may be neuroprotective due to its ability to neutralize free radicals upon NMDA receptor activation thus, reducing lipoperoxidation mediated by glutamate-induced excitotoxicity.

• Smiles:

  O=C1N ([Se]C=2C1=CC=CC2) C3=CC=CC=C3

• Molecular Formula:

  C13H9NOSe

• Molecular Weight:

  274.18

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  60940-34-3