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DHODH-IN-25

CAT: 0931-T86189-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T86189-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2619531-95-0
Target
Dehydrogenase, DNA/RNA Synthesis
Related Pathways
Cell Cycle/Checkpoint, Metabolism, DNA Damage/DNA Repair
Bioactivity
DHODH-IN-25 (Compound 25) serves as an orally active inhibitor of dihydroorotate dehydrogenase (DHODH), exhibiting a potent IC50 of 5.4 nM against human DHODH. It is applicable in research related to acute myeloid leukemia (AML) [1].
Smiles
O([C@H](C(F)(F)F)C)C1=C(C(NC2=C(Cl)C=CC=C2F)=O)C=C(F)C(NC(=O)N3C(CO)CCC3=O)=C1
Molecular Formula
C22H19ClF5N3O5
Molecular Weight
535.85
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

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HY-163328DHODH-IN-25
GTR15132929Lentiviral mouse Dhodh shRNA (UAS) - Lentiviral mouse Dhodh shRNA (UAS) (25)
GTR15093713Lentiviral human DHODH shRNA (UAS) - Lentiviral human DHODH shRNA (UAS) (25)
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GTR15132935Lentiviral mouse Dhodh shRNA (UAS) - Lentiviral mouse Dhodh shRNA (UAS, RFP) (25)
GTR15132938Lentiviral mouse Dhodh shRNA (UAS) - Lentiviral mouse Dhodh shRNA (UAS, iRFP) (25)
GTR15093716Lentiviral human DHODH shRNA (UAS) - Lentiviral human DHODH shRNA (UAS, GFP) (25)
GTR15093719Lentiviral human DHODH shRNA (UAS) - Lentiviral human DHODH shRNA (UAS, RFP) (25)
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