Cryptophycin analog 1

• Target:

  ADC Cytotoxin

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Bioactivity:

  Cryptophycin analog 1, an ADC payload, exhibits anticancer activity and demonstrates cellular potency an order of magnitude greater than the approved ADC payloads MMAE and DM1 [1].

• Smiles:

  [C@@H](C)([C@@]1([C@H](O1)C2=CC=C(CN)C=C2)[H])[C@]3(OC(=O)[C@H](CC(C)C)OC(=O)C(C)(C)CNC(=O)[C@@H](CC4=CC(Cl)=C(OC)C=C4)NC(=O)\C=C\C3)[H]

• Molecular Formula:

  C37H48ClN3O8

• Molecular Weight:

  698.24

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1260431-28-4