CD 10899

CAT: 0931-T86023-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T86023-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1331770-20-7
Target
PLK
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
CD 10899, a hydroxylated metabolite of Volasertib, is pharmacologically active against Polo-like kinase 1 (PLK1) with an IC50 of 6 nM. Volasertib is an orally active, highly potent, and ATP-competitive PLK1 inhibitor. CD 10899 can be used for cancer research [1].
Smiles
C(C)(C)N1C=2C(N(C)C(=O)C1(CC)O)=CN=C(NC3=C(OC)C=C(C(N[C@H]4CC[C@@H](CC4)N5CCN(CC6CC6)CC5)=O)C=C3)N2
Molecular Formula
C34H50N8O4
Molecular Weight
634.81
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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