CD 10899

• Target :

  PLK

• Related Pathways :

  Cell Cycle/Checkpoint

• Bioactivity :

  CD 10899, a hydroxylated metabolite of Volasertib, is pharmacologically active against Polo-like kinase 1 (PLK1) with an IC50 of 6 nM. Volasertib is an orally active, highly potent, and ATP-competitive PLK1 inhibitor. CD 10899 can be used for cancer research [1].

• Smiles :

  C(C)(C)N1C=2C(N(C)C(=O)C1(CC)O)=CN=C(NC3=C(OC)C=C(C(N[C@H]4CC[C@@H](CC4)N5CCN(CC6CC6)CC5)=O)C=C3)N2

• Molecular Formula :

  C34H50N8O4

• Molecular Weight :

  634.81

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1331770-20-7