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Abd110

CAT: 0931-T85540-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T85540-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3021581-79-0
Target
ATM/ATR, PROTACs
Related Pathways
PROTAC, DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling
Bioactivity
Abd110 (compound 42i), a Lenalidomide-based PROTAC ATR kinase degrader, selectively reduces levels of ATR and phospho-ATR while not impacting the related kinases ATM and DNA-PKcs [1].
Smiles
O=C(NC=1C=CC=CC1)C=2N=C(C=NC2N)C3=CC=C(C=C3)S(=O)(=O)NCCCCCC(=O)NCCCC#CC4=CC=CC=5C(=O)N(CC45)C6C(=O)NC(=O)CC6
Molecular Formula
C41H42N8O7S
Molecular Weight
790.89
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19235723-01Abd110

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