PBD dimer-2

• Target :

  ADC Cytotoxin

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Bioactivity :

  PBD dimer-2 (compound 2c), a C8-linked pyrrolobenzodiazepine dimer, has the capability to span an extra base pair and cross-link the 5?-Pu-GA (T/A) TC-Py sequence. It serves as a potential payload for antibody–agent conjugates (ADCs) and is under research for cancer treatments [1] [2].

• Smiles :

  O=C1C=2C(=CC(OCCCCCOC3=C(OC)C=C4C(=C3)N=C[C@]5(N(C4=O)CCC5)[H])=C(OC)C2)N=C[C@]6(N1CCC6)[H]

• Molecular Formula :

  C31H36N4O6

• Molecular Weight :

  560.64

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  145325-57-1