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PBD dimer-2

CAT: 0931-T84765-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T84765-01Size:10 mg
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CAS Number
145325-57-1
Target
ADC Cytotoxin
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
PBD dimer-2 (compound 2c), a C8-linked pyrrolobenzodiazepine dimer, has the capability to span an extra base pair and cross-link the 5?-Pu-GA (T/A) TC-Py sequence. It serves as a potential payload for antibody–agent conjugates (ADCs) and is under research for cancer treatments [1] [2].
Smiles
O=C1C=2C(=CC(OCCCCCOC3=C(OC)C=C4C(=C3)N=C[C@]5(N(C4=O)CCC5)[H])=C(OC)C2)N=C[C@]6(N1CCC6)[H]
Molecular Formula
C31H36N4O6
Molecular Weight
560.64
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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