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(R, S, S) -VH032

CAT: 0931-T84747-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T84747-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2230826-33-0
Target
Ligand for E3 Ligase, Others
Related Pathways
PROTAC, Others
Bioactivity
(R, S, S) -VH032 is a ligand for E3 ligase and a VHL/HIF-1α interaction inhibitor utilized in the synthesis of PROTACs, particularly the tau-targeting small molecule PROTAC C004019 [1]. As a VHL ligand, it recruits von Hippel-Lindau (VHL) proteins, facilitating the development of targeted protein degradation therapies.
Smiles
C(NCC1=CC=C(C=C1)C=2SC=NC2C)(=O)[C@@H]3N(C([C@H](C(C)(C)C)N)=O)C[C@@H](O)C3
Molecular Formula
C22H30N4O3S
Molecular Weight
430.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C