Itacnosertib (hydrocholide)

CAT: 0931-T84696-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T84696-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2409543-84-4

Target

TGF-beta/Smad, PI3K, ALK, FLT, Akt, Others, mTOR, JAK, STAT

Related Pathways

JAK/STAT signaling, Others, PI3K/Akt/mTOR signaling, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Angiogenesis, Cytoskeletal Signaling, Stem Cells

Bioactivity

Itacnosertib hydrochloride acts as an inhibitor targeting JAK2, ACVR1 (ALK2), and ALK5 [1].

Smiles

O(C)C1=C(C=CC(NC=2N=C(NC3=C(N=CC=C3)C4=CC=CC=N4)C=CN2)=C1)N5CCN(C)CC5.Cl

Molecular Formula

C26H29ClN8O

Molecular Weight

505.01

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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