VU 0546110

• CAS Number :

  1421523-00-3

• Target :

  Others|||Potassium Channel

• Related Pathways :

  Others|||Membrane transporter/Ion channel

• Bioactivity :

  VU 0546110, a selective inhibitor of the sperm-specific potassium channel SLO3 (IC50= 64 ?M), demonstrates 40-fold selectivity over SLO1. It effectively blocks both heterologous SLO3 currents and endogenous K+ currents, inhibiting sperm hyperpolarization and preventing hyperactivated mobility.

• Smiles :

  COC1=CC=C(SCC2CCN(CC2)C(=O)CC2=CC=C(C=C2)S(=O)(=O)C(C)C)C=C1

• Molecular Formula :

  C24H31NO4S2

• Molecular Weight :

  461.64

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C