VU-29

• CAS Number :

  890764-36-0

• Target :

  GluR

• Related Pathways :

  Neuroscience

• Purity :

  0.9963

• Bioactivity :

  VU-29 is a positive allosteric mGlu5 receptor modulator with an EC50 of 9 nM and a Ki of 244 nM for rmGluR5. It is selective for mGluR5 relative to other mGluR subtypes [EC50: rmGluR1/rmGluR2=557 nM/1.5 ?M; hmGluR4=154 nM].

• Smiles :

  N(C(=O)C1=CC=C(N(=O)=O)C=C1)C=2N(N=C(C2)C3=CC=CC=C3)C4=CC=CC=C4

• Molecular Formula :

  C22H16N4O3

• Molecular Weight :

  384.39

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C