SLU-10482

CAT: 0931-MF-0100298-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0100298-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2755451-45-5
Target
Others|||Parasite
Related Pathways
Others|||Microbiology/Virology
Bioactivity
SLU-10482, an antiparasitic agent, effectively reduces C. parvum parasitic load in HCT-8 cells with an EC50 value of 0.07 µM. It exhibits lower affinity for human ether-a-go-go (hERG; Kd = 43 µM) compared to its counterpart, SLU-2633. When administered in vivo at dosages of 5 and 15 mg/kg twice daily, SLU-10482 significantly decreases fecal oocyst counts in mice infected with C. parvum.
Smiles
FC(F)(F)C1=C(F)C=CC(CC(N2CCN(C3=NN4C(C=C3)=NN=C4)CC2)=O)=C1
Molecular Formula
C18H16F4N6O
Molecular Weight
408.35
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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