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SP-A (196-215) (human) TFA

CAT: 0931-T83847-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T83847-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Bioactivity
Surfactant protein A (SP-A) (196-215) is a synthetic peptide derived from the C-terminal carbohydrate recognition domain of human SP-A, specifically amino acids 196-215. This peptide suppresses LPS-induced TNF-α release in JAWSII mouse dendritic cells at 1 and 10 μM concentrations and promotes phagocytosis of P. aeruginosa at a 75 μM concentration. Furthermore, intratracheal administration of SP-A (196-215) at a dose of 50 μg per animal reduces disease severity and lung colony-forming units in mice infected with P. aeruginosa.
Smiles
[H]NCC(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@@H](CO)C(N[C@H](C(NCC(N[C@]([C@@H](C)O)([H])C(N1CCC[C@H]1C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@]([C@@H](C)O)([H])C(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CCC(O)=O)C(O)=O)=O)=O)=O)CC2=CC=C(O)C=C2)=O)CC3=CNC4=C3C=CC=C4)=O)=O)=O)CC5=CC=C(O)C=C5)=O)=O)=O)=O)=O)=O)CC(O)=O)=O)=O)CC6=CC=C(O)C=C6)=O)=O)CC7=CC=CC=C7)=O)CC(O)=O)=O.OC(C(F)(F)F)=O
Molecular Formula
C107H145N29O35.XCF3COOH
Molecular Weight
2397.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C