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SQLE-IN-1

CAT: 0931-T83658-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-T83658-01Size:1 mL - 10 mM (in DMSO)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1019169-83-5
Target
Akt, PTEN, PI3K, Antifungal
Related Pathways
Microbiology/Virology, Cytoskeletal Signaling, PI3K/Akt/mTOR signaling
Purity
0.9989
Bioactivity
SQLE-IN-1 is a squalene epoxidase (SQLE) inhibitor with anti-tumor activity. It can inhibit the proliferation and migration of liver cancer cell line Huh7, inhibit the production of cellular cholesterol, and increase the expression of the tumor suppressor gene PTEN. expression, inhibiting the protein expression of PI3K and AKT.
Smiles
O=S(=O)(NC1=CC=C(C=C1)NC=2N=C(N=C(C2)NC3=CC=C(C=C3)C)C)C4=CC=C(F)C=C4F
Molecular Formula
C24H21F2N5O2S
Molecular Weight
481.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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