SQLE-IN-1

• Target :

  Akt|||PTEN|||PI3K|||Antifungal

• Related Pathways :

  Microbiology/Virology|||Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling

• Purity :

  0.9989

• Bioactivity :

  SQLE-IN-1 is a squalene epoxidase (SQLE) inhibitor with anti-tumor activity. It can inhibit the proliferation and migration of liver cancer cell line Huh7, inhibit the production of cellular cholesterol, and increase the expression of the tumor suppressor gene PTEN. expression, inhibiting the protein expression of PI3K and AKT.

• Smiles :

  O=S(=O)(NC1=CC=C(C=C1)NC=2N=C(N=C(C2)NC3=CC=C(C=C3)C)C)C4=CC=C(F)C=C4F

• Molecular Formula :

  C24H21F2N5O2S

• Molecular Weight :

  481.52

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1019169-83-5