A3373

CAT: 0931-T83226-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T83226-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2324948-66-3

Target

Phospholipase

Related Pathways

Metabolism

Bioactivity

A3373 is a novel inhibitor targeting both Phospholipase D1 (PLD1) and Phospholipase D2 (PLD2), demonstrating half maximal inhibitory concentrations (IC50) of 325 nM for PLD1 and 15.15μM for PLD2. This compound effectively suppresses lipopolysaccharide (LPS) -induced immune responses and is implicated in key processes of autoimmune arthritis, bone demineralization, and osteoclastogenesis [1] [2].

Smiles

O=C(NC=1C=C(C=C(C1)C(F)(F)F)C(F)(F)F)C2=CC=3C=C(F)C=CC3N2

Molecular Formula

C17H9F7N2O

Molecular Weight

390.26

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Alternative Products

Catalog	Name
PC1006514-01	A3373

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