ATIC-IN-1

CAT: 0931-T82950-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T82950-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1402453-15-9

Target

Others

Related Pathways

Others

Bioactivity

ATIC-IN-1 (compound 14) is an inhibitor targeting the dimerization of Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC), with a K i of 685 nM. This dimerization is crucial for the enzyme's AICAR transformylase function. Additionally, ATIC-IN-1 exhibits anti-tumor properties by reducing cell proliferation and cell division rates [1].

Smiles

[C@@H](CC1=CC=C(N(=O)=O)C=C1)(NC([C@H](CCCNC(=N)N)NC(C)=O)=O)C(N(CC)CC)=O

Molecular Formula

C21H33N7O5

Molecular Weight

463.53

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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GTR19217836-01	ATIC-IN-1
BUP20833-01	ATIC-IN-1 acetate
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307143-01	ATIC
P33300	PExpress-1-Atic (rat)
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