ATIC-IN-1

• Target:

  Others

• Related Pathways:

  Others

• Bioactivity:

  ATIC-IN-1 (compound 14) is an inhibitor targeting the dimerization of Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC), with a K i of 685 nM. This dimerization is crucial for the enzyme's AICAR transformylase function. Additionally, ATIC-IN-1 exhibits anti-tumor properties by reducing cell proliferation and cell division rates [1].

• Smiles:

  [C@@H](CC1=CC=C(N(=O)=O)C=C1)(NC([C@H](CCCNC(=N)N)NC(C)=O)=O)C(N(CC)CC)=O

• Molecular Formula:

  C21H33N7O5

• Molecular Weight:

  463.53

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1402453-15-9