CC-3060

CAT: 0931-T82767-02Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0931-T82767-02Size:50 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

444288-86-2

Target

Ligand for E3 Ligase, Others

Related Pathways

Others, PROTAC

Bioactivity

CC-3060 is a potent Cereblon modulator that facilitates the degradation of ZBTB16, exhibiting a DC50 of 0.47 nM in HT-1080 cells. It orchestrates ZBTB16 degradation by targeting discrete structural degrons within various zinc finger domains [1].

Smiles

O=C1NC(=O)C(N2C(=O)C=3C=CC=C(NCC=4OC=5C=CC=CC5C4)C3C2=O)CC1

Molecular Formula

C22H17N3O5

Molecular Weight

403.39

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

4-(1-Benzofuran-2-ylmethylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione

CAS Number	444288-86-2
PubChem CID	21988575
IUPAC Name	4-(1-benzofuran-2-ylmethylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
Molecular Formula	C22H17N3O5
Molecular Weight	403.4
XLogP	2.6
Topological Polar Surface Area	109
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	4
Heavy Atom Count	30
Formal Charge	0
Complexity	755

SMILES

C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCC4=CC5=CC=CC=C5O4

InChI

InChI=1S/C22H17N3O5/c26-18-9-8-16(20(27)24-18)25-21(28)14-5-3-6-15(19(14)22(25)29)23-11-13-10-12-4-1-2-7-17(12)30-13/h1-7,10,16,23H,8-9,11H2,(H,24,26,27)

InChIKey

GRICLJZNEMDVMA-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 444288-86-2

CID: 21988575

Formula: C22H17N3O5

MW: 403.4

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	403.4
XLogP3	2.6
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	4
Exact Mass	403.11682065
Monoisotopic Mass	403.11682065
Topological Polar Surface Area	109 Å²
Heavy Atom Count	30
Formal Charge	0
Complexity	755
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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Alternative Products

Catalog	Name
HY-153698-01	CC-3060
MPM00300	mmu-miR-3060 Primers
HY-R02906-01	Mmu-miR-3060-5p mimic
1211515	3060-6005, Reducer Connector, Straight
HY-RI02906A-01	Mmu-miR-3060-5p antagomir
HY-R02905-01	Mmu-miR-3060-3p mimic
MPM01107	mmu-miR-3060-5p Primers
MIM01669	mmu-miR-3060 miRNA Inhibitor
GTR19063678-01	Ccβ
HY-RI02905A-01	Mmu-miR-3060-3p antagomir

CC-3060

Chemical Information

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