Folate-MS432

• Target:

  PROTACs

• Related Pathways:

  PROTAC

• Bioactivity:

  Folate-MS432 is a PROTAC that degrades MEKs selectively in cancer cells via folate receptor-dependent pathways.

• Smiles:

  C([C@@H](NC(CCCCCCCCCCNCCCONC(=O)C1=C(NC2=C(F)C=C(I)C=C2)C(F)=C(F)C=C1)=O)C(C)(C)C)(=O)N3[C@H](C(N[C@@H](C)C4=CC=C(C=C4)C=5SC=NC5C)=O)C[C@@H](OC(CCCCN6C=C(CNC(CC[C@H](NC(=O)C7=CC=C(NCC=8N=C9C(NC8)=NC(N)=NC9=O)C=C7)C(O)=O)=O)N=N6)=O)C3

• Molecular Formula:

  C77H94F3IN18O12S

• Molecular Weight:

  1679.65

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2769735-56-8