MS432

• Target :

  PROTACs|||MEK

• Related Pathways :

  MAPK|||PROTAC

• Bioactivity :

  MS432 is a highly selective PD0325901-based VHL-recruiting PROTAC degrader for MEK1 and MEK2.

• Smiles :

  O=C(N[C@@H](C)C1=CC=C(C=C1)C2=C(N=CS2)C)[C@H]3C[C@@H](O)CN3C([C@@H](NC(CCCCCCCCCCNCCCONC(C4=CC=C(C(F)=C4NC5=CC=C(C=C5F)I)F)=O)=O)C(C)(C)C)=O

• Molecular Formula :

  C50H65F3IN7O6S

• Molecular Weight :

  1076.06

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C