J5 peptide

• Bioactivity:

  J5 peptide, an MBP inhibitor, competitively inhibits the binding of MBP 85-99 to HLA-DR2, and mitigates PLP 139-151/MBP 85-99-induced experimental autoimmune encephalomyelitis (EAE) in mice. It is utilized in research pertaining to inflammatory and immune diseases [1].

• Smiles:

  C([C@@H](NC([C@H](CCC(O)=O)N)=O)CCCCN)(=O)N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N3[C@H](C(N[C@H](C(O)=O)C)=O)CCC3)C)=O)C)=O)C)=O)C)=O)CCCCN)=O)=O)C)=O)CCC(O)=O)=O)[C@@H](C)C)=O)CCCCN)=O)CCC1

• Molecular Formula:

  C70H114N18O21

• Molecular Weight:

  1543.76

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  444305-16-2