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Ontorpacept

CAT: 0931-T81605-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T81605-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2131089-46-6
Target
Others
Related Pathways
Others
Bioactivity
Ontorpacept (TTI-621) is a soluble fusion protein comprising the N-terminal (1-118) of human SIRPα fused to the Fc region of human IgG1. This N-terminal (1-118) segment serves as the binding domain for CD47, an inhibitor of macrophage-mediated phagocytosis. As a checkpoint inhibitor that blocks CD47, ontorpacept exhibits antitumor activity [1].
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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