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PKCd (8-17)

CAT: 0931-T81451-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T81451-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
379711-25-8
Target
PKC
Related Pathways
Cytoskeletal Signaling, Chromatin/Epigenetic
Bioactivity
PKCd (8-17) is a bioactive peptide originating from the V1 domain of protein kinase C (PKC) d. It impedes phorbol 12-myristate 13-acetate (PMA) -stimulated PKCd translocation and activation, which mitigates ischemic injury in cardiac and cerebral cells, promotes fibroblast proliferation, and suppresses graft coronary artery disease in [mouse models].
Smiles
[C@H](CC1=CC=C(O)C=C1)(C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)CO)=O)=O)CC(C)C)=O)CCC(O)=O)=O)NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=CC=C2)NC([C@H](CO)N)=O)=O)CC(N)=O)=O)CO)=O
Molecular Formula
C50H73N11O18
Molecular Weight
1116.18
Shipping Conditions
Ice Packs
Storage Temperature
-20°C