PKCd (8-17)

• CAS Number :

  379711-25-8

• Target :

  PKC

• Related Pathways :

  Cytoskeletal Signaling|||Chromatin/Epigenetic

• Bioactivity :

  PKCd (8-17) is a bioactive peptide originating from the V1 domain of protein kinase C (PKC) d. It impedes phorbol 12-myristate 13-acetate (PMA) -stimulated PKCd translocation and activation, which mitigates ischemic injury in cardiac and cerebral cells, promotes fibroblast proliferation, and suppresses graft coronary artery disease in [mouse models].

• Smiles :

  [C@H](CC1=CC=C(O)C=C1)(C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)CO)=O)=O)CC(C)C)=O)CCC(O)=O)=O)NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=CC=C2)NC([C@H](CO)N)=O)=O)CC(N)=O)=O)CO)=O

• Molecular Formula :

  C50H73N11O18

• Molecular Weight :

  1116.18

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C