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SRC-1 (686-700)

CAT: 0931-T81106-02Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T81106-02Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
394658-24-3
Target
Glucocorticoid Receptor
Related Pathways
Endocrinology/Hormones
Bioactivity
SRC-1 (686-700) is a bioactive peptide encompassing amino acids 686 to 700, which include the second LXXLL motif from NR box II of steroid receptor coactivator [SRC1]. These coactivator proteins facilitate transcription by ligand-dependent interaction with nuclear receptors.
Smiles
C([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CN=CN1)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CN=CN2)NC([C@H](CCCNC(=N)N)N)=O)=O)CCCCN)=O)[C@H](CC)C)=O)CC(C)C)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)CC(C)C)=O)CCC(N)=O)=O)CCC(O)=O)=O)=O)CO)(=O)N3[C@H](C(N[C@H](C(O)=O)CO)=O)CCC3
Molecular Formula
C77H131N27O21
Molecular Weight
1771.03
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

H-Arg-His-Lys-Ile-Leu-His-Arg-Leu-Leu-Gln-Glu-Gly-Ser-Pro-Ser-OH
CAS Number394658-24-3
PubChem CID168510734
IUPAC Name(4S)-4-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-oxopentanoyl]amino]-5-[[2-[[(2S)-1-[(2S)-2-[[(1S)-1-carboxy-2-hydroxyethyl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-5-oxopentanoic acid
Molecular FormulaC77H131N27O21
Molecular Weight1771.0
XLogP-10.5
Topological Polar Surface Area795
Hydrogen Bond Donor Count26
Hydrogen Bond Acceptor Count27
Rotatable Bond Count60
Heavy Atom Count125
Formal Charge0
Complexity3650
SMILES
CC[C@H](C)[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CO)C(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC3=CN=CN3)NC(=O)[C@H](CCCN=C(N)N)N
InChI
InChI=1S/C77H131N27O21/c1-9-42(8)61(103-66(115)46(16-10-11-23-78)93-70(119)53(30-43-32-85-37-90-43)97-62(111)45(79)15-12-24-87-76(81)82)73(122)101-52(29-41(6)7)69(118)100-54(31-44-33-86-38-91-44)71(120)94-47(17-13-25-88-77(83)84)64(113)98-51(28-40(4)5)68(117)99-50(27-39(2)3)67(116)96-49(19-21-58(80)107)65(114)95-48(20-22-60(109)110)63(112)89-34-59(108)92-55(35-105)74(123)104-26-14-18-57(104)72(121)102-56(36-106)75(124)125/h32-33,37-42,45-57,61,105-106H,9-31,34-36,78-79H2,1-8H3,(H2,80,107)(H,85,90)(H,86,91)(H,89,112)(H,92,108)(H,93,119)(H,94,120)(H,95,114)(H,96,116)(H,97,111)(H,98,113)(H,99,117)(H,100,118)(H,101,122)(H,102,121)(H,103,115)(H,109,110)(H,124,125)(H4,81,82,87)(H4,83,84,88)/t42-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,61-/m0/s1
InChIKey
PWWHDKSQHIXQJP-QHGNQABOSA-N
Chemical Structure
2D Structure
2D structure of H-Arg-His-Lys-Ile-Leu-His-Arg-Leu-Leu-Gln-Glu-Gly-Ser-Pro-Ser-OH
CAS: 394658-24-3
CID: 168510734
Formula: C77H131N27O21
MW: 1771.0
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight1771.0
XLogP3-10.5
Hydrogen Bond Donor Count26
Hydrogen Bond Acceptor Count27
Rotatable Bond Count60
Exact Mass1770.00128430
Monoisotopic Mass1770.00128430
Topological Polar Surface Area795 Ų
Heavy Atom Count125
Formal Charge0
Complexity3650
Isotope Atom Count0
Defined Atom Stereocenter Count15
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
HY-P5458SRC-1 (686-700)
CRB1001143-01Steroid Receptor Coactivator-1 (SRC-1) (686-700)
CRB1001143-01Steroid Receptor Coactivator-1 (SRC-1) (686-700) - (Peptide)
CRB1000545-01SRC-1 (676-700)
CRB1000545-01SRC-1 (676-700) - (Peptide)
GTR18894385SRC-1 (676-700), biotinylated
GTR19346478-01Biotin-SRC-1 (676–700) TFA
CRB1001376-01Biotin Steroid Receptor Coactivator-1 (SRC-1) (676-700)
CRB1001376-01Biotin Steroid Receptor Coactivator-1 (SRC-1) (676-700) - (Biotin Labeled)
BNUM0686-50Estrogen Receptor beta 1 (ESR2/686), 1mg/mL

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