α-Conotoxin MrIC

• Target:

  AChR

• Related Pathways:

  Neuroscience

• Bioactivity:

  ?-Conotoxin MrIC is a biased agonist selective for the ?7 nicotinic acetylcholine receptor (nAChR), with activation contingent upon the presence of type II positive allosteric modulators, such as PNU120596. It is utilized to investigate neurological disorders and delineate the pharmacological characteristics of the ?7nAChR [1].

• Smiles:

  O=C1N2[C@@](CCC2)(C(=O)N[C@@H](C)C(=O)N[C@@]3(C(=O)N[C@@H](CC4=CN=CN4)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N5[C@](C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(N)=O)CSSC[C@@](C(=O)N[C@@]([C@@H](C)O)(C(=O)N[C@H]1CC6=CN=CN6)[H])(NC(=O)[C@@H](NC([C@@H](NC(=O)[C@@H]7CCCN7)CCC(O)=O)=O)CSSC3)[H])(CCC5)[H])[H])[H]

• Molecular Formula:

  C74H111N23O24S4

• Molecular Weight:

  1835.07

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1417816-41-1