α-Conotoxin PIA

• Target :

  AChR

• Related Pathways :

  Neuroscience

• Bioactivity :

  Selective antagonist of ?6-containing nicotinic receptors that discriminates between the closely related ?6 and ?3 subunits (IC50 values are 0.95 and 74.2 nM for rat ?6/?3?2?3 and ?3?2 receptors respectively) .

• Smiles :

  O=C1N2[C@](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@H](C(N)=O)CSSC[C@@]3(NC(=O)[C@@H](NC(=O)[C@H]4N(C([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CC(O)=O)=O)CCC4)CSSC[C@@](C(=O)N[C@@]([C@@H](C)O)(C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC5=CN=CN5)C(=O)N[C@H]1CC(N)=O)[H])(NC(=O)[C@H](C(C)C)NC(=O)[C@]6(N(C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC3=O)CCC6)[H])[H])[H])[H])(CCC2)[H]

• Molecular Formula :

  C79H125N27O25S4

• Molecular Weight :

  1981.3

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  669050-68-4