S3 Fragment

• Target :

  LIM Kinase

• Related Pathways :

  Cell Cycle/Checkpoint

• Bioactivity :

  S3 Fragment is a biologically active peptide featuring the amino-terminal phosphorylation site unique to Xenopus ADF/cofilin, which is the target of LIM kinase (LIMK) phosphorylation. LIMK1, a pivotal regulator of the actin cytoskeleton, phosphorylates ADF/cofilin at serine-3, leading to its inactivation. As a segment of the S3 peptide harboring the serine-3 sequence, this fragment serves as a widely recognized competitive inhibitor of LIMK1.

• Molecular Formula :

  C73H120N18O24S2

• Molecular Weight :

  1697.97

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C