S3 Fragment

S3 Fragment

• UNSPSC Description: S3 Fragment is a biological active peptide. (This peptide contains the unique amino-terminal phosphorylation site of Xenopus ADF/cofilin, the LIM kinase (LIMK) phosphorylation site. LIMK1 is a key regulator of the actin cytoskeleton through its phosphorylation of ADF/cofilin at serine-3 for inactivation. This peptide is a fragment of the S3 peptide containing the serine-3 sequence of ADF/cofilin that has been widely used as an effective competitive inhibitor of LIMK1.)
• Target Antigen: LIM Kinase (LIMK)
• Type: Peptides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-Kinase/protease
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/s3-fragment.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N[C@@H](C)C(N[C@@H](CO)C(NCC(N[C@@H](C(C)C)C(N[C@@H](CCSC)C(N[C@@H](C(C)C)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(N)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCSC)N
• Molecular Weight: 1697.97
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported