ProTx-III

• Target:

  Sodium Channel

• Related Pathways:

  Membrane transporter/Ion channel

• Bioactivity:

  ProTx-III, a spider venom peptide derived from the Peruvian green velvet tarantula, functions as a selective and potent inhibitor of the voltage-gated sodium channel Na v 1.7, exhibiting an IC 50 of 2.1 nM. Characterized by its inhibitor cystine knot motif (ICK), ProTx-III can attenuate the pain response and is applicable in research on chronic pain, epilepsy, and arrhythmia [1].

• Molecular Formula:

  C162H246N52O43S6

• Molecular Weight:

  3802.4

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C