ProTx III

• Description:

  Potent Nav1.7 blocker (IC50 = 2.5 nM) . Also inhibits Nav1.1, Nav1.2, Nav1.3 and Nav1.6 in the nanomolar range. Exhibits no effects on Cav channels or nAChR at 5 μM. Demonstrates analgesic activity in vivo; antagonizes effects of scorpion-venom toxin OD1 at Nav1.7.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  3802.41

• Molecular Formula:

  C162H246N52O43S6

• Notes:

  Research use only, not for human use.

• Receptor:

  ——