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M190S

CAT: 0931-T79747-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T79747-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2578300-07-7
Target
Caspase
Related Pathways
Proteases/Proteasome, Apoptosis
Bioactivity
M109S is a novel small molecule that protects cells from mitochondria-dependent apoptosis, demonstrating efficacy both in vitro and in vivo. It shows promise as a research tool for studying cell death mechanisms and could lead to therapeutics targeting the mitochondria-dependent cell death pathway. M109S possesses oral bioactivity and excellent brain permeability [1].
Smiles
N([C@@H](C)C1=CC=C(C=C1)C2=NC(=NO2)C3CC3)C4=C5C(=NC(C)=N4)OC(C)=C5
Molecular Formula
C21H21N5O2
Molecular Weight
375.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

N-[(1S)-1-[4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)phenyl]ethyl]-2,6-dimethylfuro[2,3-d]pyrimidin-4-amine
CAS Number2578300-07-7
PubChem CID155460647
IUPAC NameN-[(1S)-1-[4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)phenyl]ethyl]-2,6-dimethylfuro[2,3-d]pyrimidin-4-amine
Molecular FormulaC21H21N5O2
Molecular Weight375.4
XLogP4.4
Topological Polar Surface Area89.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Heavy Atom Count28
Formal Charge0
Complexity539
SMILES
CC1=CC2=C(N=C(N=C2O1)C)N[C@@H](C)C3=CC=C(C=C3)C4=NC(=NO4)C5CC5
InChI
InChI=1S/C21H21N5O2/c1-11-10-17-19(23-13(3)24-21(17)27-11)22-12(2)14-4-8-16(9-5-14)20-25-18(26-28-20)15-6-7-15/h4-5,8-10,12,15H,6-7H2,1-3H3,(H,22,23,24)/t12-/m0/s1
InChIKey
HKRGAACOQSQCIC-LBPRGKRZSA-N
Chemical Structure
2D Structure
2D structure of N-[(1S)-1-[4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)phenyl]ethyl]-2,6-dimethylfuro[2,3-d]pyrimidin-4-amine
CAS: 2578300-07-7
CID: 155460647
Formula: C21H21N5O2
MW: 375.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight375.4
XLogP34.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Exact Mass375.16952493
Monoisotopic Mass375.16952493
Topological Polar Surface Area89.9 Ų
Heavy Atom Count28
Formal Charge0
Complexity539
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BA3394-1M190S

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