PK-10

• Target :

  Antifungal|||Others|||Mitochondrial Metabolism

• Related Pathways :

  Microbiology/Virology|||Others|||Metabolism

• Bioactivity :

  PK-10, when combined with Fluconazole, exhibits potent synergistic antifungal activity against multiple Fluconazole-resistant Candida albicans strains. This compound impedes hyphae formation, stimulates reactive oxygen species accumulation, and inflicts mitochondrial membrane potential damage. Consequently, PK-10 decreases cellular ATP levels and induces mitochondrial dysfunction [1].

• Molecular Formula :

  C35H36F3N5O

• Molecular Weight :

  599.69

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C