PK-10

• Target:

  Antifungal|||Others|||Mitochondrial Metabolism

• Related Pathways:

  Microbiology/Virology|||Others|||Metabolism

• Bioactivity:

  PK-10, when combined with Fluconazole, exhibits potent synergistic antifungal activity against multiple Fluconazole-resistant Candida albicans strains. This compound impedes hyphae formation, stimulates reactive oxygen species accumulation, and inflicts mitochondrial membrane potential damage. Consequently, PK-10 decreases cellular ATP levels and induces mitochondrial dysfunction [1].

• Molecular Formula:

  C35H36F3N5O

• Molecular Weight:

  599.69

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C