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PK-10

CAT: 0931-T79709-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79709-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Antifungal, Others, Mitochondrial Metabolism
Related Pathways
Microbiology/Virology, Others, Metabolism
Bioactivity
PK-10, when combined with Fluconazole, exhibits potent synergistic antifungal activity against multiple Fluconazole-resistant Candida albicans strains. This compound impedes hyphae formation, stimulates reactive oxygen species accumulation, and inflicts mitochondrial membrane potential damage. Consequently, PK-10 decreases cellular ATP levels and induces mitochondrial dysfunction [1].
Molecular Formula
C35H36F3N5O
Molecular Weight
599.69
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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