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SSE1806

CAT: 0931-T79708-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T79708-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Apoptosis, Others, Microtubule Associated
Related Pathways
Apoptosis, Others, Cytoskeletal Signaling
Bioactivity
SSE1806, a podophyllotoxin derivative (a natural antimitotic agent), functions as a microtubule/tubulin inhibitor, exhibiting potent anticancer and antiproliferative properties. It demonstrates a GI50 for inhibiting cancer cell growth between 1.29-21.15 μM. This compound induces mitotic disruption and G2/M phase arrest, upregulates p53 expression, and suppresses the growth of colon cancer organoids. Notably, SSE1806 can counteract multidrug resistance in cell lines that overexpress MDR-1 [1].
Molecular Formula
C21H18N2O5
Molecular Weight
378.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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