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Antileishmanial agent-22

CAT: 0931-T79633-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79633-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Parasite, Antibacterial
Related Pathways
Microbiology/Virology
Bioactivity
Antileishmanial agent-22 (compound 15b) acts as an antiparasitic and antibacterial agent, demonstrating activity against Leishmania (IC50 = 0.408 μM), malaria, and tuberculosis. It functions via an antifolate mechanism, inhibiting folic and folinic acids with 88% and 94% efficacy at 100 μM. The compound inhibits P. berghei by 96.67% in vivo/in vitro at 48.4 μM/kg/day and 0.038 μM (IC50), and it inhibits M. tuberculosis with an MIC of 28.44 μM [1].
Molecular Formula
C29H26Cl2N4O3
Molecular Weight
549.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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