AChE/Aβ-IN-1

CAT: 0931-T79569-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T79569-01Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Target

Others, Cholinesterase (ChE), Beta Amyloid, iGluR

Related Pathways

Neuroscience, Others, Membrane transporter/Ion channel

Bioactivity

AChE/Aβ-IN-1 (compound 32) is a potent, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 86 nM and an NMDA receptor antagonist targeting the GluN1-1b/GluN2B subunit combination with an IC50 of 3.876 μM. It also impedes Aβ aggregation, exhibits favorable blood-brain barrier permeability, offers neuroprotection, and enhances cognitive and spatial memory in rat models [1].

Molecular Formula

C20H25BrN4

Molecular Weight

401.34

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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HY-155733	AChE/Aβ-IN-1
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AChE/Aβ-IN-1

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