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IRAK4-IN-25

CAT: 0931-T79447-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79447-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
IRAK
Related Pathways
NF-κB, Immunology/Inflammation
Bioactivity
IRAK4-IN-25 (compound 38), a potent oral IRAK4 inhibitor (IC50 = 7.3 nM) with low clearance (Cl = 12 mL/min/kg), effectively suppresses pro-inflammatory cytokine production and demonstrates favorable in vitro safety and ADME profiles. It is suitable for research on inflammatory and autoimmune disorders [1].
Molecular Formula
C23H25N5O4
Molecular Weight
435.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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