IRAK4-IN-16

CAT: 0931-T24174-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T24174-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1812188-83-2

Target

IRAK, Others

Related Pathways

Immunology/Inflammation, Others, NF-κB

Bioactivity

IRAK4-IN-16 (compound 4) is a potent inhibitor of interleukin-1 receptor associated kinase 4 (IRAK4) with an IC50 of 2.5 nM. It exhibits cytotoxicity against OCI-LY10, TMD8, Ramos, and HT cells, with IC50 values of 0.2, 0.2, 0.6, and 2.7 μM, respectively [1].

Smiles

C(NC=1C(C(F)F)=NN(C)C1)(=O)C2=C3N(N=C2)C=CC(N[C@@H]4CCCNC4)=N3

Molecular Formula

C17H20F2N8O

Molecular Weight

390.39

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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MBS5773925	IRAK4-IN-16
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IRAK4-IN-16

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