JET-209

CAT: 0931-T79230Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T79230Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Histone Acetyltransferase|||PROTACs
Related Pathways
Chromatin/Epigenetic|||PROTAC
Bioactivity
JET-209 is a potent proteolysis-targeting chimera (PROTAC) that effectively degrades CBP/p300, exhibiting half-maximal degradation concentration (DC50) values of 0.05 nM for CBP and 0.2 nM for p300. The compound comprises lenalidomide (the cereblon ligand), a connecting linker, and GNE-207 (the bromodomain inhibitor) . JET-209 is utilized in cancer research [1].
Molecular Formula
C46H47N9O6
Molecular Weight
821.92
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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