ML 209

• Target:

  ROR

• Related Pathways:

  Metabolism

• Purity:

  0.9987

• Bioactivity:

  ML-209 is an antagonist of retinoic acid receptor-related orphan receptor ?t (ROR?t; IC50= 1.1 ?M in a reporter assay) .1It inhibits ROR?t-induced transcription in HEK293T cells expressing the human receptor (IC50= 300 nM) . ML-209 inhibits ROR?t-dependent differentiation of isolated na?ve cord blood human CD4+T cells into Th17 T helper cells.

• Smiles:

  C (CC (=O) N1C[C@@H] (C) C[C@@H] (C) C1) (C2=C (OC) C=C (OC) C=C2O) C=3C=C4C (=CC3) OCO4

• Molecular Formula:

  C25H31NO6

• Molecular Weight:

  441.52

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1334526-14-5