ML 209

• CAS Number :

  1334526-14-5

• Target :

  ROR

• Related Pathways :

  Metabolism

• Purity :

  0.9987

• Bioactivity :

  ML-209 is an antagonist of retinoic acid receptor-related orphan receptor ?t (ROR?t; IC50= 1.1 ?M in a reporter assay) .1It inhibits ROR?t-induced transcription in HEK293T cells expressing the human receptor (IC50= 300 nM) . ML-209 inhibits ROR?t-dependent differentiation of isolated na?ve cord blood human CD4+T cells into Th17 T helper cells.

• Smiles :

  C(CC(=O)N1C[C@@H](C)C[C@@H](C)C1)(C2=C(OC)C=C(OC)C=C2O)C=3C=C4C(=CC3)OCO4

• Molecular Formula :

  C25H31NO6

• Molecular Weight :

  441.52

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C