Products for Research Use Only

CDK4/6-IN-17

CAT: 0931-T79112-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T79112-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2035069-96-4
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
CDK4/6-IN-17 (compound 12) is an orally bioavailable inhibitor of CDK4/6, exhibiting potent activity with IC50 values between 10-100 nM in BE (2) cells, and has demonstrated efficacy in inhibiting tumor growth in the COLO205 xenograft model [1].
Smiles
C(F)(F)[C@H]1N2C=3C(N=C2CC1)=C(F)C=C(C3)C4=NC(NC5=CC=C(CN6CCN(CC)CC6)C=N5)=NC=C4F
Molecular Formula
C27H28F4N8
Molecular Weight
540.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Popular Products