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LSD1-UM-109

CAT: 0931-T78888-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T78888-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2252446-26-5
Target
Histone Demethylase
Related Pathways
Chromatin/Epigenetic
Bioactivity
LSD1-UM-109 is a highly potent and reversible inhibitor of LSD1, demonstrating an IC50 of 3.1 nM. This compound exhibits strong antiproliferative activity, inhibiting cell growth with IC50 values of 0.6 nM in the MV4;11 acute leukemia cell line and 1.1 nM in the H1417 small-cell lung cancer cell line [1].
Smiles
C(N1C=2C(=C(C(=NC2)C=3C=C4C(=CC3)N(C)N=C4)C5=CC(F)=C(C#N)C=C5)C=C1)C6(C)CCNCC6
Molecular Formula
C29H27FN6
Molecular Weight
478.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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