LSD1-UM-109

• Target:

  Histone Demethylase

• Related Pathways:

  Chromatin/Epigenetic

• Bioactivity:

  LSD1-UM-109 is a highly potent and reversible inhibitor of LSD1, demonstrating an IC50 of 3.1 nM. This compound exhibits strong antiproliferative activity, inhibiting cell growth with IC50 values of 0.6 nM in the MV4;11 acute leukemia cell line and 1.1 nM in the H1417 small-cell lung cancer cell line [1].

• Smiles:

  C(N1C=2C(=C(C(=NC2)C=3C=C4C(=CC3)N(C)N=C4)C5=CC(F)=C(C#N)C=C5)C=C1)C6(C)CCNCC6

• Molecular Formula:

  C29H27FN6

• Molecular Weight:

  478.56

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2252446-26-5