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PD07

CAT: 0931-T78739-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T78739-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Cholinesterase (ChE), Others
Related Pathways
Neuroscience, Others
Bioactivity
PD07 is an orally active acetylcholinesterase (AChE) inhibitor, exhibiting an IC50 of 0.29 μM against human AChE, and demonstrates inhibition of cholinesterases (ChEs), β-site amyloid precursor protein cleaving enzyme 1 (BACE1) with an IC50 of 13.42 μM, as well as Aβ1–42 aggregation in vitro. Additionally, PD07 possesses antioxidant properties with a DPPH radical inhibition IC50 value of 26.46 μM and has been shown to ameliorate memory and cognitive deficits in scopolamine-induced amnesic rats. This compound is relevant for Alzheimer's disease research [1].
Molecular Formula
C23H21ClN2O4
Molecular Weight
424.88
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-149340PD07

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