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MKA031

CAT: 0931-T78716-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T78716-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2951012-00-1
Target
MIF, Others
Related Pathways
Others, Immunology/Inflammation
Bioactivity
MKA031 (compound 6y) is a non-competitive inhibitor of macrophage migration inhibitory factor (MIF) with an IC50 of 1.7 μM. It disrupts the MIF-aryl hydrocarbon receptor interacting protein (AIF) interaction, impedes MIF nuclear translocation, and mitigates N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) -induced cell death. MKA031 is applicable in research on chronic hepatitis C virus infection [1].
Smiles
O=C(NCC=1SC=CC1)C=2N=NN(C2)C3=CC=C(C=C3)C(=O)NC=4C=CC=CC4
Molecular Formula
C21H17N5O2S
Molecular Weight
403.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
MBS5820378MKA031

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