Products for Research Use Only

A-77636

CAT: 0931-T78644-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T78644-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
778546-51-3
Target
Dopamine Receptor
Related Pathways
GPCR/G Protein, Neuroscience
Bioactivity
A-77636 is a potent, selective, and long-acting oral dopamine D1 receptor agonist with an effective concentration (EC50) of 1.1 nM and a corresponding pEC50 value of 8.13. It demonstrates the highest affinity for the dopamine D1 receptor with a dissociation constant (Ki) of 39.8 nM and a pKi of 7.40 ± 0.09. Notably, A-77636 exhibits antiparkinsonian activity [1].
Smiles
C(N)[C@@H]1O[C@H]([C@]23CC4(CC(C2)(CC(C3)(C4)[H])[H])[H])CC=5C1=CC=C(O)C5O
Molecular Formula
C20H27NO3
Molecular Weight
329.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C