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Firazorexton hydrate

CAT: 0931-T78636-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T78636-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2861934-86-1
Target
OX Receptor, Others, ERK
Related Pathways
Neuroscience, GPCR/G Protein, Others, MAPK
Bioactivity
Firazorexton hydrate (TAK-994) is a brain-penetrant, orally active agonist of the orexin type 2 receptor (OX2R) with a potent EC50 of 19 nM, effectively reducing wakefulness fragmentation and cataplexy-like episodes in mouse models of narcolepsy [1].
Smiles
C([C@@H]1N(C(C(C)(C)O)=O)CC[C@@H]1NS(C)(=O)=O)C2=C(F)C(=CC=C2)C3=CC(F)=CC(F)=C3.O
Molecular Formula
C22H25F3N2O4S.3/2H2O
Molecular Weight
497.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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