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JG-23

CAT: 0931-T78533-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T78533-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2640819-75-4
Target
Others, Microtubule Associated
Related Pathways
Cytoskeletal Signaling, Others
Bioactivity
JG-23, a 4-chloro-modified analog, effectively induces t-tau degradation and demonstrates robust metabolic stability, exhibiting an extended half-life (T1/2) of 36 minutes in mouse liver microsome assays [1].
Smiles
CN1/C(/SC=2C1=CC(Cl)=CC2)=C\3/C(=O)N(CC)\C(=C\C=4C=CN=CC4)\S3
Molecular Formula
C19H16ClN3OS2
Molecular Weight
401.93
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

CID 164625273
CAS Number2640819-75-4
PubChem CID164625273
IUPAC Name(2Z,5E)-5-(5-chloro-3-methyl-1,3-benzothiazol-2-ylidene)-3-ethyl-2-(pyridin-4-ylmethylidene)-1,3-thiazolidin-4-one
Molecular FormulaC19H16ClN3OS2
Molecular Weight401.9
XLogP4.5
Topological Polar Surface Area87
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Heavy Atom Count26
Formal Charge0
Complexity632
SMILES
CCN1/C(=C/C2=CC=NC=C2)/S/C(=C/3\N(C4=C(S3)C=CC(=C4)Cl)C)/C1=O
InChI
InChI=1S/C19H16ClN3OS2/c1-3-23-16(10-12-6-8-21-9-7-12)26-17(18(23)24)19-22(2)14-11-13(20)4-5-15(14)25-19/h4-11H,3H2,1-2H3/b16-10-,19-17+
InChIKey
LIWXAIDHVWIEQV-SRNIGAPGSA-N
Chemical Structure
2D Structure
2D structure of CID 164625273
CAS: 2640819-75-4
CID: 164625273
Formula: C19H16ClN3OS2
MW: 401.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight401.9
XLogP34.5
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass401.0423322
Monoisotopic Mass401.0423322
Topological Polar Surface Area87 Ų
Heavy Atom Count26
Formal Charge0
Complexity632
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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