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PVZB1194

CAT: 0931-T78125-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T78125-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1141768-04-8
Target
Kinesin
Related Pathways
Cytoskeletal Signaling
Bioactivity
PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis through inhibiting Eg5 ATPase activity. It binds to the α4/α6 allosteric pocket and demonstrates ATP-competitive activity [1].
Smiles
O=S(=O)(N)C1=CC=C(C=C1)C=2C=CC(=C(F)C2)C(F)(F)F
Molecular Formula
C13H9F4NO2S
Molecular Weight
319.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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