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PD-L1-IN-2

CAT: 0931-T78053-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T78053-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2894733-91-4
Target
PD-1/PD-L1
Related Pathways
Cell Cycle/Checkpoint, Apoptosis, Immunology/Inflammation
Bioactivity
PD-L1-IN-2, a Naamidine J derivative, serves as a promising antineoplastic immunomodulator by hindering PD-L1 activity. In vivo studies indicate that it suppresses PD-L1 expression and amplifies tumor-infiltrating T-cell response, thus exerting anticancer effects. This compound is particularly utilized in the investigation of colorectal cancer [1].
Smiles
O=C(OC(C)(C)C)NC1=CC=CC(=C1)C(=O)NC2=NC(=C(N2C)CC3=CC=C(OC)C(OC)=C3)CC4=CC=C(OC)C=C4
Molecular Formula
C33H38N4O6
Molecular Weight
586.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C