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PAMP-12 (unmodified) acetate

CAT: 0931-T78027L-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T78027L-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others, Adrenergic Receptor
Related Pathways
Neuroscience, GPCR/G Protein, Others
Purity
0.9897
Bioactivity
PAMP-12 (unmodified) acetate is an endogenous peptide and potent agonist of the MRGPRX2 (MrgX2) receptor with an EC50 ranging from 20 to 50 nM. PAMP-12 (unmodified) mediates hypotensive effects by inhibiting catecholamine secretion from sympathetic nerve endings and adrenal chromaffin cells, serving as a critical tool in the study of neuroimmune interactions and cardiovascular regulation.
Smiles
N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CC(N)=O)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)=O)=O)CC2=CNC3=CC=CC=C23)=O)=O)=O)CC4=CNC5=CC=CC=C45)=O)=O)=O)=O.CC(O)=O
Molecular Formula
C77H118N24O15.xC2H4O2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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