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MC-VA-PAB-Exatecan

CAT: 0931-T77854Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T77854Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2680543-57-9
Target
Drug-Linker Conjugates for ADC, Topoisomerase
Related Pathways
Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair
Bioactivity
MC-VA-PAB-Exatecan is a drug-linker conjugate used for synthesising ADCs, containing an ADC linker (MC-VA-PAB) and the topoisomerase I inhibitor Exatecan, which exhibits antitumour activity.
Smiles
N(C(OCC1=CC=C(NC([C@@H](NC([C@@H](NC(CCCCCN2C(=O)C=CC2=O)=O)[C@@H](C)C)=O)C)=O)C=C1)=O)[C@@H]3C4=C5C(C=6N(C5)C(=O)C7=C(C6)[C@](CC)(O)C(=O)OC7)=NC=8C4=C(CC3)C(C)=C(F)C8
Molecular Formula
C50H54FN7O11
Molecular Weight
948.02
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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